Buy Tramadol online- the drug effects and interaction

You cannot buy Tramadol online and use it at the same time with drugs that depress the central nervous system (sedatives). Tramadol causes an increased sedative effect, especially if the drug contains ethanol.

Also, you cannot use it simultaneously with Quinidine, since this drug can cause an increase in the concentration of Tramadol and end up in overdose. If you constantly use a narcotic analgesic at the same time as barbiturate, you may reduce the effectiveness of both drugs.

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Action of the drug

Tramadol has the effect of an opium analgesic. They produce the following effect on the patient’s body:

  • inhibition of the passage of pain impulses through the nervous system;
  • opening of calcium and potassium channels; increase in the effect of sedatives;
  • activation of opioid-type receptors in the brain and spinal cord.

The complex effect of Tramadol helps almost completely get rid of pain, because even the spinal cord can be affected by the opium analgesic. Due to the strong narcotic effect, the drug is included in the priority list for drug control in the country.

To buy Tramadol online is not recommended to be consumed simultaneously with alcoholic beverages or alcohol-based drugs. Simultaneous use of alcohol and drugs leads to increased side effects:

  • hallucinations;
  • disorders of consciousness;
  • lack of coordination;
  • hypertensions;
  • increased nervous excitability; and other effects that are characteristic of a person in a state of alcoholic or narcotic intoxication.

If the patient uses vital alcohol-based drugs, it is recommended to replace them with alcohol-free analogues if possible. If this cannot be done, you should consult the doctor who prescribed the drug or a similar specialist. They can make one of the following decisions:

  • temporarily reduce the dosage of the alcohol-based drug;
  • reduce the number of drug doses per month;
  • temporarily cancel the drug by replacing it with a similar one.

You cannot completely cancel important drugs, as this can lead to a sharp deterioration of health and even gives the risk of death. If a patient who is prescribed Tramadol is prone to alcoholism, it is very important to monitor their behavior and not allow them to drink alcohol.

Permissible use of the drug during pregnancy and breastfeeding

Doctors allow to buy Tramadol online both when carrying a child and breastfeeding a baby. However, in both cases, it is important to be careful.

To a lesser extent, Tramadol affects the child when breastfeeding. Then the percentage of the substance that comes to the baby does not exceed 0.1%. However, this percentage can negatively affect the child’s condition. If you notice allergic reactions in the absence of complementary foods, obvious disorders of the nervous system (insomnia, apathy or increased activity), it is important to consult a specialist.

During pregnancy, it is not recommended to use the drug, because it enters the placenta in small doses and can cause addiction in the embryo. A short course of the drug is allowed if the pain causes the mother severe stress, which is even more dangerous for the child.

Use for women during pregnancy and lactation

In the first trimester of pregnancy, the use of Tramadol is strictly prohibited. In the second and third trimesters, the drug can be prescribed only in exceptional cases, under conditions that minimize the risk of complications in the fetus. The active substance penetrates the placenta and can cause abnormalities in the development of internal organs, bones and the central nervous system (CNS) of the child.

During lactation, the drug can be used once, if absolutely necessary. You do not need to take a break from breastfeeding, but the first portion of milk is decanted and not used.

Special instructions

Tramadol should be used with extreme caution:

  • for kidney and liver diseases
  • in patients with traumatic brain injury with increased intracranial pressure in patients with epilepsy
  • opioid addicts
  • for abdominal pain of unknown origin (acute abdomen)
  • confusion of unclear origin
  • in case of violations of the respiratory center or respiratory function in a state of shock

In patients taking Tramadol at the recommended doses, seizures were noted, the risk of which may be increased if the recommended maximum daily dose (400 mg) is exceeded.


To achieve an overdose state, you can use more than 8 mg of the drug per kilogram of body weight. Thus, the maximum allowable dosage of 400 mg, which is used for moderate pain, is contraindicated in patients weighing up to 50 kg: it can cause an overdose.

If you follow the dosages specified by the specialist, only too frequent administration of the drug can lead to an overdose. This is especially true for older people, who have an increased duration of excretion of the drug from the body (more than 8 hours). The drug does not immediately lead to the maximum degree of overdose, at first you may not notice the symptoms of the violation at all. Depending on how much the permissible dose was exceeded, symptoms of three stages of poisoning develop:

First stage. It is expressed by the typical symptoms of poisoning: nausea and increased sweating, a decrease in heart rate and a decrease in blood pressure. There is rarely a slight fever. The patient may notice dizziness, headaches, black dots, blurred vision.

Second stage. Respiratory disorders begin. The patient breathes shallowly, heavily. The heartbeat continues to deteriorate, there is a narrowing of the pupils. There is severe abdominal pain. Diarrhea may occur. It becomes difficult to move, and the body reactions are noticeably slowed down.

Third stage. Convulsions and other symptoms of epilepsy may occur, and edema of the lungs or larynx often occurs. Suffocation or spasm of the lungs begins, which can lead to loss of consciousness. CNS depression often ends in coma. If you do not help the patient, it can be fatal.

This overdose is not compensated by gastric lavage. If you find symptoms of exceeding the permissible dose, you need to consult a doctor so that they quickly compensate for the dangerous condition with the help of detoxification and special drugs.

Since overdose threatens to fall into a coma and death, you must carefully follow the doctor’s instructions and not to buy Tramadol online. This is especially true for the elderly. They cannot just follow the instructions in the package: it is important to visit a specialist, so that he professionally and individually prescribed a course of therapy.

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